Projects

 

  • Imaging Instrumentation Laboratory
  • Ongoing Projects
  • Line Scanner X-Ray: High Resolution (up to 50 μm) full body X-ray imaging solution.
  • SYNCBOX: A fully automated system to reduce R&D time on x-ray devices, able to control all x-ray equipment’s with a hardware controller combined with software systems. Able to upgrade each system with low cost
  • Industrial X-Ray NDT System: A fully automated nondestructive X-ray testing equipment for continuous manufacturing. Uses low dose continuous X-ray pulses to obtain X-ray data through a conveyor. Investigates the cracks and production errors on several products, such as welded pipes or circuit boards.
  • Dual Energy Direct Digital X-Ray System: Uses Synchronized Image Acquisition to improve image contrast and quality, lowers the radiation dose. Generates multiple energy X-rays to obtain high contrast, and tissue-specific images through a DR system. Includes the development all the necessary parts including software, GUI, hardware, embedded systems, mechanics, motorized controls. Creates low dose sequences for patient health, and faster acqusion time
  • Low Dose Portable Dental X-Ray System: A complete intra-oral dental system with 3D imaging, low dose and advanced image processing tools. Includes the design of the systems that help dentists take easier X-ray images and get higher quality results.
  • Dual Energy DR X-Ray System: Is the fusion of X-ray with MRI. Priori MR images of the subject are overlaid on top of the live images acquired during X-Ray fluoroscopy. Project has a wide usage on cardiac interventional operatio
  • Completed Projects
  • TAM: Researcher and Academician Development Center in Telecommunications an Informatics (Funding: National Planing Agency of Turkey (DPT))
  • MR Image Fusion Sytem Development for X-Ray Flouroscopic Interventions (Funding: TÜBITAK )
  • A Novel Integrated Optoelectronic System for Automatic Catheter Localization in Interventional MRI (Funding: TÜBITAK )
  • Investigation of the Neuro-vascular Coupling in the Brain: The study of the BOLD Counterparts of Steady-State Evoked Potentials using EEG-fMRI technique (Funding: TÜBITAK )
  • National Magnetic Resonance Imaging Research Center (UMRAM) (Funding: National Planing Agency of Turkey (DPT)
  • University-Industry Collaboration Project on Magnetic Resonance Imaging (SIEMENS Medical Solutions)
  • Examination of Local Cardiac Motion and Perfusion using MRI (TÜBITAK Project)
  • Deformable Surface models and Their applications in cardiac Magnetic Resonance Imaging  (TÜBITAK-GSRT International Funding)
  • Examination of Cardiac Perfusion with MR Imaging  (Bogazici University Research Fund Project)

 

  • Cellular Imaging & Electrophysiology Laboratory
  • Ongoing Projects
  • Dil İşleme ve Görsel İşleme Görevlerinin Beyin Üzerindeki Lateralize Etkisinin Kulak Sıcaklığı ve İYKAS ile İncelenmesi (Boğaziçi  University BAP Grant)
  • Suda ve Yağda Eriyen Vitaminlerin Nörona Farklılaştırılmış SH-SY5Y Hücrelerinde Apoptoz Koşullarına Karşı Koruyucu Etkilerinin İncelenmesi (Boğaziçi University BAP Grant)
  • Compeleted Projects
  • Foundation of Molecular and Cellular Imaging Laboratory (Moleküler ve Hücresel Görüntüleme Laboratuvarı Alt Yapı Projesi) ( Bogazici University Research Fund)
  • Investigation of an Alzheimer‘s Disease Model in Rat by Behavioral, Immunohistochemical and Electrophysiological Methods (Sıçanda bir Alzheimer Hastalıðı Modelinin Davranışsal, ımmünohistokimyasal ve Elektrofizyolojik Yöntemlerle ıncelenmesi) (Bogazici University Research Fund)
  • Generation of Reactive Oxygen Species and Nitric Acid in Experimental Alzheimer Disease Model and their Role in Apoptosis/Necrosis (Deneysel Alzheimer Hastalığı Modelinde Reaktif Oksijen Türleri ve Nitrik Asitin Hasar Oluşturucu Etkileri ile Apoptoz/Nekroz Oluşumundaki Rollerinin ıncelenmesi) (Marmara University Research Fund)
  • Generation of Reactive Oxygen Species and Nitric Acid in Experimental Huntington Disease Model and their Role in Apoptosis/Necrosis (Deneysel Huntington Hastalığı Modelinde Reaktif Oksijen Türleri ve Nitrik Asitin Hasar Oluşturucu Etkileri ile Apoptoz/Nekroz Oluşumundaki Rollerinin ıncelenmesi)( Marmara University Research Fund)
  • Patch clamp Tight-seal Whole Cell Recording of Spontaneous and Miniature Current Activities from Rat Living Hippocampal Slices and Change Observed during Cardiac Arrest ( Sıçan Beyni Canlı Hipokampal Kesitlerinden Spontan ve Minyatür Akım Aktivitelerinin Tek Hücre Düzeyinde Ölçülmesi ve Bu Aktivitelerde Kalp Durması Koşullarında Oluşan Deðişikliðin Gözlenmesi) ( Bogazici University Research Fund)

 

  • Computational Imaging Laboratory
  • Ongoing Projects
  • Development of diagnostic products that can demonstrate genetic, metabolic and histopathologic features of glial brain tumors as non-invasive with magnetic resonance imaging (TÜBITAK 1003 Grants (2017-2020))
  • 1H Bilateral, Flexible Breast RF Coil Design for Magnetic Resonance Imaging Systems (TÜBITAK 1001 Grants (2017-2019) 
  • Completed Projects
  • Determination of Multimodality Magnetic Resonance Imaging Based Biomarkers for Mild Cognitive Impairment in Parkinson Disease (TÜBITAK 1001 Grant. 2015-2018.)
  • Investigation of the Human Brain Metabolism in-vivo in Chronic Liver Failure Using Magnetic Resonance Spectroscopic Editing Techniques (Bogazici BAP Grant. 2015-2018.)
  • Feasibilty Study of Obtaining High-Resolution Spectroscopy Images Using Data Fusion Techniques (Royal Society Newton Mobility Grants (2016-2017) )
  • Fast Phosphorus Magnetic Resonance Spectroscopic Imaging using Compressed Sensing for Imaging Brain Tumors (TÜBITAK 3501 National Young Researchers Career Development Program (CAREER), 2012-2014)
  • Phosphorus MR Spectroscopic Imaging of Brain Tumors at 3T (31P_SPECTRA_3T) (Marie Curie International Reintegration Grant (IRG), 2010- 2014)

 

  • Biomechanics Laboratory
  • Ongoing Projects
  • Towards a novel and comprehensive muscular mechanics paradigm: finite element model development and analyses (TÜBITAK, 2018-ongoing)
  • Comprehensive Experimental Assessment of Previously Unknown Effects of Botulinum Toxin on Muscle Function (TÜBITAK, 2017-ongoing)
  • Completed Projects
  • Assessment of mechanics of spastic muscle with intraoperative experiments: developing novel approaches to show that limited joint motion is caused by an integral abnormal functioning of the muscle-connective tissue system,  (TUBITAK,2013 - 2016)
  • Investigation of the effects of Botox on muscular mechanics at the level of a whole muscle compartment using finite element analyses (Bogaziçi University Research Fund, 2013 - 2016)
  • Analysis of human muscular mechanics in vivo using magnetic resonance imaging (TUBITAK, 2011 - 2014)
  • Assessment of the effects of botox on mechanics of the target muscle and non-targteted muscles of an entire muscle compartment in experimental conditions close to in vivo (Bogaziçi University Research Fund, 2011 - 2015)
  • Testing of spastic human knee flexor muscles intraoperatively: asssessment of muscle mechanics and the acute effects of remedial surgery (Bogaziçi University Research Fund, 2009 - 2012)
  • Assessment of the effects of botox used in the treatment of pathologies causing limited joint range of motion on muscular mechanics (TUBITAK, 2009 - 2011)
  • Assessment of the biomechanical effects of hamstring tendon graft harvesting for ACL reconstruction on muscle force (TUBITAK, 2006 - 2009)
  • Investigation of physiology of muscle with experimental methods  (Bogaziçi University Research Fund, 2004 - 2008)
  • Investigation of the acute effects of aponeurotomy using finite element modeling (Bogaziçi University Research Fund, 2004 - 2009)

 

  • Biodesign Laboratory
  • Ongoing Projects
  •  MRG Altında Görüntülenebilen Yeni Nesil Prostat Biyopsi Ignesi ve Yardımcı Robotik Sistem Tasarımı, (TÜBITAK (2015 - ongoing)
  • Prostat Kanseri ve Sinir Hücreleri Arasındaki İlişkiyi İncelemek İçin Mikro-çip Tasarımı ( μPCa SISTEM )(Yüksekögretim Kurumları tarafından destekli bilimsel arastırma projesi (2017 – ongoing))
  •  Safe Ultrasound Tranmission Lines for MRI Catheters (2014-ongoing)
  • Completed Projects
  • Perifer Damar Tıkanıklıklarına Baglı Rahatsızlıkların Tedavisi için Hiper Perfüzyon Katateri Gelistirilmesi (Yüksekögretim Kurumları tarafından destekli bilimsel arastırma projesi (2016 – 2017))
  • Kisiye Özel Endovasküler Stent (Funded by TÜBITAK (2014 – 2017))
  • Erken Kanser Teshisinde in vivoHücre Görüntülenmesi Yapabilen Kateter Tasarımı ve Üretimi (TÜBITAK (2013 – 2016))
  • Pediyatrik hastalarda MR altında perkütan konjenital kalp rahatsızlıklarının tedavisinde kullanılmak üzere 5 Fr aktif klavuz katater tasarımı (TÜBITAK (2013 – 2016))
  • EEG fNIRS ölçümleri için Optimal Prob Gelistirilmesi (Yüksekögretim Kurumları tarafından destekli bilimsel arastırma projesi (2013 – 2015))